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PUBLICATION

2024

A model H5N2 vaccine strain for dual protection against H5N1 and H9N2
avian influenza viruses

Jin-Ha Song, Seung-Eun Son, Ho-Won Kim, Se-Hee An, Chung-Young Lee, Hyuk-Joon Kwon *, Kang-Seuk Choi *

Under review

Rapid and specific on-site H5Nx avian influenza diagnosis via RPA and PAM-independent CRISPR-Cas12a assay combined with anti-NP antibody-based viral RNA purification

JINHA SONG, Seung-Eun Son, Se-Hee An, Chung-Young Lee, Ho-Won Kim, Seung-Ji Kim, Hyuk-Joon Kwon and Kang-Seuk Choi

Under review

H-NS is a Transcriptional Repressor of the CRISPR-Cas System in Acinetobacter baumannii ATCC 19606

Kyeongmin Kim, Md Maidul Islam, Seunghyeok Bang, Jeongah Kim, Chung-Young Lee, Je Chul Lee, Minsang Shin

Journal of Microbiology, 62, 2024

Emergence of HPAI H5N6 Clade 2.3.4.4b in Wild Birds: A Case Study From South Korea, 2023

Chang-Gi Jeong, Chung-Young Lee, Su-Beom Chae, Jung-Hoon Kwon, Eun-Jee Na, Park-Jun Soo, Young-Sik Kim, Seung-Chai Kim, Hwan-Ju Kim, Young-Sun Sung, Sun-Young Kim, Won-Il Kim, Jae-Ku Oem

Transboundary and Emerging Diseases, 2024

(2023 Impact factor=3.5, JIF percentile=93.7)

Exploring Potential Intermediates in the Cross-Species Transmission of Influenza A Virus to Humans

Chung-Young Lee

Viruses 2024, 16(7), 1129 

(2023 Impact factor=3.8, JIF percentile=59.8)

Dispensable role of wild rodents in avian influenza A virus transmission in Gyeonggi province, Korea

Chung-Young Lee*, Ilhwan Kim, Hyuk-Joon Kwon*

Korean Journal of Veterinary Research 2024;64(2):e13

Major shift of influenza A virus of swine (IAV-S) by human-to-swine spillover of the 2009 pandemic virus in Korea

Seung-Chai Kim, Taek Geun Lee, Eun-Jee Na, Sung-Hyun Moon, Hwan-Ju Kim, Chang-Gi Jeong, Young Ki Choi, Yeonsu Oh, Chung-Young Lee*, Jae-Ku Oem*, Won-Il Kim*, Ho-Seong Cho*

*Co-corresponding

Transboundary and Emerging Diseases, 2024

(2023 Impact factor=3.5, JIF percentile=93.7)

Host Subcellular Organelles: Targets of Viral Manipulation

Min Seok Song, Dong-Kun Lee, Chung-Young Lee, Sang-Cheol Park, Jinsung Yang
International Journal of Molecular Sciences 25(3), 1638

2023

Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks
Katie E Holmes, David VanInsberghe, Lucas M Ferreri, Baptiste Elie, Ketaki Ganti, Chung-Young Lee, Anice C Lowen
bioRxiv

Evolution and international transmission of H3N2 canine influenza A viruses from Korea during 2014-2017
Chung-Young Lee
Journal of Veterinary Science
24, e78
(2022 Impact factor=1.8)

Engineering an Optimal Y280-Lineage H9N2 Vaccine Strain by Tuning PB2 Activity
Se-Hee An, Seung-Min Hong, Jin-Ha Song, Seung-Eun Son, Chung-Young Lee, Kang-Seuk Choi, Hyuk-Joon Kwon 
Int. J. Mol. Sci  24(10), 8840
(2021 Impact factor=6.208
)

Epistasis reduces fitness costs of influenza A virus escape from stem-binding antibodies
Lee, Chung-Young; Caceres, C Joaquin; Geiger, Ginger; Seibert, Brittany; Faccin, Flavio Cargnin; Gay, L Claire; Ferreri, Lucas M; Kaul, Drishti; Wrammert, Jens; Tan, Gene S
PNAS 120(17), e2208718120
(2021 Impact factor=12.779)


       2023년 한빛사 인터뷰

2022

Beneficial effects of cellular coinfection resolve inefficiency in influenza A virus transcription
Shartouny, Jessica R*; Lee, Chung-Young*; Delima, Gabrielle K; Lowen, Anice C
PLoS Pathogens 18 (9), e1010865,
DOI: https://doi.org/10
.1371/journal.ppat.1010865, *Contributed equally

(2021 Impact factor=7.464, JIF percentile=91.03)

        2022년 한빛사 소개

Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission
Ganti, Ketaki*; Ferreri, Lucas M*; Lee, Chung-Young*; Bair, Camden R*; Delima, Gabrielle K; Holmes, Kate E; Suthar, Mehul S; Lowen, Anice C
PLoS Pathogens 18 (3), e1010181

DOI: https://doi.org/10.1371/journal.ppat.1010181
*Contributed equally

(2021 Impact factor=7.464, JIF percentile=91.03)

Selection of an Optimal Recombinant Egyptian H9N2 Avian Influenza Vaccine Strain for Poultry with High Antigenicity and Safety
An, Se-Hee, Son, Seung-Eun, Song, Jin-Ha, Hong, Seung-Min, Lee, Chung-Young, Lee, Nak-Hyung, Jeong, Young-Ju, Choi, Jun-Gu, Lee, Youn-Jeong, Kang, Hyun-Mi
Vaccines 10 (2), 162
DOI: https://doi.org/10.3390/vaccines10020162

(2021 Impact factor=4.961)

Before
2022

Animal models for SARS-CoV-2
Lee, Chung-Young, Lowen, Anice C
Current opinion in virology 48, 73-81
DOI: https://doi.org/10.1016/j.coviro.2021.03.009


Collective interactions augment influenza A virus replication in a host-dependent manner
Phipps, Kara L; Ganti, Ketaki*; Jacobs, Nathan T*; Lee, Chung-Young*; Carnaccini, Silvia; White, Maria C; Manandhar, Miglena; Pickett, Brett E; Tan, Gene S; Ferreri, Lucas M;
Nature microbiology 5 (9), 1158-1169,
DOI: https://doi.org/10.1038/s41564-020-0749-2  

*Contributed equally

Rank orders of mammalian pathogenicity-related PB2 mutations of avian influenza A viruses
Lee, Chung-Young; An, Se-Hee; Choi, Jun-Gu; Lee, Youn-Jeong; Kim, Jae-Hong; Kwon, Hyuk-Joon;
Scientific Reports 10 (1), 1-13
DOI: https://doi.or
g/10.1038/s41598-020-62036-5 

Improvement of PR8-Derived Recombinant Clade 2.3. 4.4 c H5N6 Vaccine Strains by Optimization of Internal Genes and H103Y Mutation of Hemagglutinin
An, Se-Hee; Hong, Seung-Min; Son, Seung-Eun; Song, Jin-Ha; Lee, Chung-Young; Choi, Jun-Gu; Lee, Youn-Jeong; Jeong, Jei-Hyun; Kim, Jun-Beom; Song, Chang-Seon 
Vaccines 8 (4), 781
DOI: https://doi.org/10.3390/vaccines8040781
 

Generation of highly productive and mammalian nonpathogenic recombinant H9N2 avian influenza viruses by optimization of 3’end promoter and NS genome
An, Se-Hee; Lee, Chung-Young; Choi, Jun-Gu; Lee, Youn-Jeong; Kim, Jae-Hong; Kwon, Hyuk-Joon
Veterinary microbiology 228, 213-218
DOI: https://doi.org/10.1016/j.vetmic.2018.11.031


Bioengineering a highly productive vaccine strain in embryonated chicken eggs and mammals from a non-pathogenic clade 2· 3· 4· 4 H5N8 strain
An, Se-Hee; Lee, Chung-Young; Hong, Seung-Min; Choi, Jun-Gu; Lee, Youn-Jeong; Jeong, Jei-Hyun; Kim, Jun-Beom; Song, Chang-Seon; Kim, Jae-Hong; Kwon, Hyuk-Joon
Vaccine 37 (42), 6154-6161
DOI: https://doi.org/10.1016/j.vaccine.2019.08.074


Novel Mutations Evading Avian Immunity around the Receptor Binding Site of the Clade 2.3. 2.1 c Hemagglutinin Gene Reduce Viral Thermostability and Mammalian Pathogenicity
An, Se-Hee; Lee, Chung-Young; Hong, Seung-Min; Song, Chang-Seon; Kim, Jae-Hong; Kwon, Hyuk-Joon 
Viruses 11 (10), 923
DOI: https://doi.org/10.3390/v11100923


Molecular evolution of Salmonella enterica subsp. enterica serovar Gallinarum biovar Gallinarum in the field
Kim, Nam-Hyung, Ha, Eun-Jin, Ko, Dae-Sung, Lee, Chung-Young, Kim, Jae-Hong, Kwon, Hyuk-Joon
Veterinary microbiology 235, 63-70
DOI: https://doi.org/10.1016/j.vetmic.2019.05.019


An optimized molecular method for detection of influenza A virus using improved generic primers and concentration of the viral genomic RNA and nucleoprotein complex
Kim, Ji-Woon*, Lee, Chung-Young*, Nguyen, Thanh Trung, Kim, Il-Hwan, Kwon, Hyuk-Joon, Kim, Jae-Hong
Journal of Veterinary Diagnostic Investigation 31 (2), 175-183
DOI: 10.1177/1040638719830760
*Contributed equally


Pathobiological and genomic characterization of a cold-adapted infectious bronchitis virus (BP-caKII)
Hong, Seung-Min, An, Se-Hee, Lee, Chung-Young, Song, Chang-Seon, Choi, Kang-Seuk, Kim, Jae-Hong, Kwon, Hyuk-Joon
Viruses 10 (11), 652
DOI: https://doi.org/10.3390/v10110652


Molecu
lar prophage typing of Staphylococcus aureus isolates from bovine mastitis
Ko, Dae-Sung, Seong, Won-Jin, Kim, Danil, Kim, Eun-Kyung, Kim, Nam-Hyung, Lee, Chung-Young; Kim, Jae-Hong; Kwon, Hyuk-Joon
Journal of Veterinary Science 19 (6), 771-781
DOI: https://doi.org/10.4142/jvs.2018.19.6.771


Acquisition of Innate Inhibitor Resistance and Mammalian Pathogenicity During Egg Adaptation by the H9N2 Avian Influenza Virus
Lee, Chung-Young, An, Se-Hee, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon
Frontiers in Microbiology 9, 1939
DOI: https://doi.org/10.3389/fmicb.2018.01939


Novel mutations in avian PA in combination with an adaptive mutation in PR8 NP exacerbate the virulence of PR8-derived recombinant influenza A viruses in mice
Lee, Chung-Young, An, Se-Hee, Kim, Ilhwan, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon
Veterinary microbiology 221, 114-121
DOI: https://doi.org/10.1016/j.vetmic.2018.05.026


Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene
Lee, Chung-Young, An, Se-Hee, Kim, Ilhwan, Go, Du-Min, Kim, Dae-Yong, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon
Scientific Reports 7 (1), 1-12
PMID: 28860593


Effect of the fourth nucleotide at the 3′ end of neuraminidase and matrix viral genomic RNA on the pathogenicity of influenza virus A/PR/8/34
Lee, Chung-Young, Kwon, Hyuk-Joon, Nguyen, Thanh Trung, Kim, Ilhwan, Jang, Hyung-Kwan, Kim, Jae-Hong
Journal of Veterinary Science 18 (Suppl 1), 307
PMID: 28859270 


Optimized clade 2.3. 2.1 c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza
Jang, Jin-Wook, Lee, Chung-Young, Kim, Il-hwan, Choi, Jun-Gu, Lee, Youn-Jeong, Yuk, Seong-Su, Lee, Ji-Ho, Song, Chang-Seon, Kim, Jae-Hong, Kwon, Hyuk-Joon
Journal of veterinary science 18 (S1), 299-306
DOI: https://doi.org/10.4142/jvs.2017.18.S1.299

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